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Stenosis of the vertebral artery (VA) in either its extra- or intracranial portions is an important cause of posterior circulation stroke. Stenosis of the vertebral artery (VA) in either its extra- or intracranial portions is an important cause of posterior circulation stroke. Talk to your doctor about the treatment that's best for your situation. Because of difficulty accessing the vertebral artery, standard treatment has been conservative in most centres. The antegrade femoral approach is a routinely used technique for the percutaneous treatment of the lower extremities vascular disease. Use today’s latest technology and methods to optimize imaging of complex skull base anatomy. 20 However, in 2007 the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS) subgroup analysis failed to show any . Patients with recently symptomatic vertebrobasilar stenosis have a high risk of recurrent stroke similar to carotid stenosis, with the highest risk in the first month. This new book provides interventional cardiologists, both as beginners or fully experienced, with a reference on all aspects of angioplasty and stenting of the carotid and supra-aortic trunks. Endarterectomy for atherosclerotic stenosis at the origin and proximal extracranial vertebral artery has been performed via a supraclavicular incision since the early 1960s, with variable success rates. The subclavian becomes the axillary artery at the lateral border of the first rib. Blocked arteries in the heart often lead to a person having a heart attack or chest pain. The purpose of this study was to evaluate the feasibility and efficacy of insertion of the closed-cell, self-expandable Carotid Wallstent for the treatment of . After reporting our initial results, the results of VA stenosis operations and the follow-up studies are analyzed. Found insideDiagnostic and angiographic images of nonatherosclerotic PAD are also included. Anyone who is engaged in or preparing to engage in endovascular work for PAD should find this book useful as a reference and as an instruction material. This handbook supplements hands-on training in interventional cardiology with a specific focus on percutaneous intervention in patients with extracranial carotid artery stenosis. Statins can help prevent the continued build up of cholesterol plaque in the artery. A 501(c)(3) non-profit organization. Blood thinners such as aspirin or clopidogrel can help prevent a clot from forming in the artery. When an artery inside the skull becomes blocked by plaque or disease, it is called cerebral artery stenosis. Vertebral artery stenosis is a major cause of posterior circulation ischemia in the elderly [].The stroke incidence in patients with vertebral artery stenosis can be as high as 10.9% [].Symptomatic vertebrobasilar artery stenosis usually has poor prognosis, with the death and permanent morbidity rate of 10% as a result of ischemic stroke even after positive drug treatment []. The narrowing of the vertebral or basilar arteries caused by atherosclerosis creates vertebrobasilar insufficiency (VBI), or an insufficient delivery of blood flow to the posterior structures of the brain. The vertebrobasilar arteries supply the cerebellum, medulla, midbrain, and occipital cortex. Patient 6. After reporting our initial results, the results of VA stenosis operations and the follow-up studies are analyzed. Carotid artery disease, also called carotid artery stenosis, is the narrowing of the carotid arteries, usually caused by atherosclerosis. Like carotid artery stenosis, vertebral artery stenosis is highly dangerous and can prevent oxygen from reaching the brain. Many pathologic processes, including atherosclerosis, trauma, fibromuscular dysplasia, dissections, and aneurysm, among others, can lead to symptoms referable to the vertebral artery. There was no evidence then navigated into the subclavian artery, and an ''angiograph- of distal vertebral or basilar artery stenosis in any patient. What is a normal internal carotid artery velocity? Naylor AR, Ricco JB, de Borst GJ, et al. What does ultrasound of carotid arteries show? © 2021 Cedars-Sinai. Vertebral Artery Stenosis These arteries supply blood to the brainstem and the cerebellum. Talk to your doctor about the treatment that's best for your situation. This plaque buildup is known as atherosclerosis. Found insideThis book will bring out the state of art of carotid stenosis in the basic and clinical approaches for better understanding of the mechanisms and useful therapies for these disease. Methods A prospective, non-randomized, single-center pilot study enrolled 30 patients with severe VAOS . The first step to treating cerebral artery stenosis is usually medication. There was no evidence then navigated into the subclavian artery, and an ''angiograph- of distal vertebral or basilar artery stenosis in any patient. This book will comprise eight main sections: (1) The Basics, (2) Arteries of the Head and Neck (3) The basics of Intracranial Arteries (4) Diseases of the vessels (5) Stroke Imaging (6) Veins Imaging (7) Spine Imaging (8) Pediatrics. Ischemic stroke A carotid ultrasound is performed to test for narrowed carotid arteries, which increase the risk of stroke. A small balloon is inserted into the tube. This article reviews the epidemiology, natural . Stenosis can occur in other parts of the body, such as the spine. Secondary prevention aims to improve the hemodynamic situation and intends to eliminate possible sources of thromboembolism. The morphology of the plaque was classified into homogeneous or heterogeneous. The used non-invasive technique is shown to have high reliability and may be used to screen patients suspected of having subclavian steal pre-angiographically and preoperatively. However, the natural history of VA stenotic lesions is not known and its . Flow in left vertebral artery (short arrows) varies between ante- grade and retrograde. This procedure is ideal for people with severe (100%) stenosis. This new, third edition of The ESC Textbook of Cardiovascular Medicine is a ground-breaking initiative from the European Society of Cardiology that transforms reference publishing in cardiovascular medicine to better serve the changing ... What are the symptoms of vertebral artery occlusion? Treatment for spinal stenosis depends on the location of the stenosis and the severity of your signs and symptoms. The safest and most effective treatment for symptomatic vertebral artery stenosis has not yet been proven. However, many lesions arise in smaller vessels with a wide variety of focal neurological deficits. All Rights Reserved. Here, we discuss the merits and pitfalls of endovascular treatment for this under . Of 26 patients treated with aspirin for a median follow-up of 19.7 months, 6 (23%) had a stroke in the same territory as the stenotic intracranial artery (2 of 13 patients [15%] with unilateral vertebral artery stenosis, 3 of 9 patients [33%] with stenosis involving the basilar artery, and 1 of 4 [25%] with PCA or PICA stenosis). Introduction. Variable restenosis rates have been reporte … Stenosis of the ostium (V0) and the proximal segment (V1) of the vertebral artery is a common cause of vertebrobasilar ischemia and an embolic source in the posterior circulation. With stenting, a self-expanding mesh tube is placed within the artery at the site of the narrowing. The narrowing can also be treated by percutaneous transluminal balloon angioplasty. Found insideA practical resource covering both elective and emergency procedures for the practicing vascular and endovascular clinician This book provides medical professionals (vascular surgeons, interventional cardiologists, interventional ... When an artery inside the skull becomes blocked by plaque or disease, it is called cerebral artery stenosis. Thoroughly revised to reflect the most recent innovations in vascular and endovascular surgery, it features more than 150 chapters on topics new to this edition, and equips residents and practitioners alike with the latest procedures and ... Carotid artery disease, also called carotid artery stenosis, is the narrowing of the carotid arteries, usually caused by atherosclerosis. fig 1.. Anteroposterior oblique views of the basilar artery. Normal healthy arteries are flexible and have smooth inner walls. As a result, when the constriction occurs hypoxia of neurons (nerve . The term retrograde blood flow describes blood that is flowing toward the heart. Purpose:To present our experience with the use of drug-eluting stents (DES) in patients with symptomatic vertebral artery ostium stenosis (VAOS).Methods:Between 2003 and 2008, 28 consecutive patien. In the population we studied, the risk of recurrent vertebrobasilar stroke under best medical treatment alone was low, questioning the need for and feasibility of a phase 3 trial. Up to a quarter of patients with vertebrobasilar ischemic stroke or TIA have a symptomatic stenosis of the vertebrobasilar arteries.1,2 Patients with vertebral artery (VA) stenosis >50% have a high risk of recurrent stroke, comparable to patients with symptomatic carotid artery stenosis, with the highest risk during the first weeks after the initial TIA or ischemic stroke.3 Endovascular . An arteriographic study of cerebrovascular disease in man. These arteries are smaller than the carotid arteries and may be buried deep inside the brain, where they are much harder for a surgeon to get to. This information is not intended as a substitute for professional medical care. Endovascular treatment of vertebral artery-origin and innominate/subclavian artery stenosis has changed in the last 15 years. I. Stenosis and occlusion of the vertebralbasilar arterial system. © 2000-2021 The StayWell Company, LLC. Stroke. 1998 Jul. New techniques and technologies that can be used in the treatment of such lesions . All rights reserved. Vertigo, dizziness, nausea, vomiting and head or neck pain are the most common initial symptoms reported. What is carotid stenosis? In human anatomy, the subclavian arteries are paired major arteries of the upper thorax, below the clavicle. _ ÈøL Carotid artery tortuosity is defined as vascular elongation leading to redundancy or an altered course. Carotid stenosis is a progressive narrowing of the carotid arteries in a process called atherosclerosis. Treatment of Vertebral Artery Stenosis. proximal to origin of left vertebral artery. endstream endobj 159 0 obj <> endobj 160 0 obj [161 0 R] endobj 161 0 obj <. Atherosclerosis or "hardening of the arteries" is the main cause of vertebrobasilar disease. Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment. This process causes the formation of an intramural hematoma, resulting in stenosis or occlusion. The book also gives an insight into the clinical manifestations of carotid and vertebral artery dissection and to the possibilities and limitations of the main diagnostic tools, ultrasound, CT and MR imaging, and angiography. The optimal management of symptomatic OVAS remains controversial. Heterogeneous plaque is composed of a mixture of hypoechoic, isoechoic, and hyperechoic lesions; homogeneous plaques consist of only 1 of these 3 types of plaque. CAD can cause thrombosis and vascular stenosis and is the major cause of stroke . This book comprehensively evaluates the impact of SES implantation on the outcomes of patients treated in the real world of interventional cardiology. Typical areas where stenosis occurs in the head and neck are the internal carotid artery, middle cerebral artery, vertebral artery, and basilar artery. Through an open incision in the skull, neurosurgeons reroute blood flow around the blocked artery using a replacement blood vessel from another part of your body. Surgical interventions include endovascular treatment and the . In human anatomy, the subclavian arteries are. A comprehensive review of vascular disease in the vertebrobasilar circulation by one of the world's leading authorities, fully updated throughout. The vertebral artery delivers blood to the neck's vertebrae, upper spinal column, the space around the outside of the skull. Stroke scoring systems to evaluate patients have been developed but are of limited use for vertebrobasilar stroke. The new edition of this medical reference book discusses everything you need to know to take full advantage of this powerful modality, from anatomy, scanning, and technique, to normal and abnormal findings and their interpretation. A, Diagram shows significant stenosis of left. Accurate selection of surgical candidates remains imprecise. Language consistent with the Guide to Physical Therapist Practice, 2nd Edition offers common linguistic ground through the use of Guide standards. Lay-flat pages and uncluttered design make the book easier to use as a quick reference. NEW! During this procedure, a tube is inserted into an artery in the groin and threaded to the narrowed artery. For patients age 80 and older, angioplasty and stenting has a higher risk of stroke than surgery (carotid endarterectomy). Carotid arteries are usually narrowed by a buildup of plaque — made up of fat, cholesterol, calcium and other substances that circulate in the bloodstream. Function. posterior tibial artery pulse by Doppler ultrasonography . If the narrowing of the artery is severe, and doesn't respond to medications or is greater than a 50% blockage, more invasive treatment may be needed. Vertebral artery origin stenosis (VAOS) is a common but underappreciated cause of stroke. A, Diagram shows significant stenosis of left subclavian artery Other common signs and symptoms include weakness, hemiparesis, ataxia, diplopia, pupillary abnormalities, speech difficulties and altered mental status. When the brain doesn't get enough oxygen, a stroke, or even death, can occur. Stenosis or occlusion involving vertebral artery (VA) origin is a significant cause of posterior circulation stroke and can result from either arterial embolus or hypoperfusion, or both 4. This device is called a stent. Death or major disability is the result of occlusion of large vessels in the vertebrobasilar system. In 2009, it was shown that there is a higher percentage of 50% or more stenosis in PCI versus ACI patients (26% vs. 11.5), which in concert with a high recurrence rate in PCI, demanded endovascular consideration. BACKGROUND: Vertebral artery origin stenosis is a known cause of stroke that is treatable with angioplasty and stenting. crease in the in-stent stenosis. According to stenting of carotid stenosis (see Treatment, p. 103), vertebral artery stenting should be preceded by dual antiplatelet therapy, e.g., 100 mg aspirin + 4 x 75 mg clopidogrel the day before the intervention and platelet aggregometry (Multiplate) performed on the day of the intervention. The extracranial vertebral artery is affected by several pathological processes that cause stroke. Choose a doctor and schedule an appointment. Found insideMost strokes are attributed to atherosclerosis of neck and intracranial arteries, brain embolism from the heart, and penetrating artery disease; these are discussed in detail in many other books. Background Drug-coated balloon (DCB) is a potential treatment for patients with low restenosis risk in vertebral artery origin stenosis (VAOS). ic roadmap'' was made of the subclavian and the vertebral FIG 2. et al. Treatment of Vertebral Artery Ostial Stenosis: a Single Center Experience Objective: To evaluate our early experience using self-expanding stents to treat atherosclerotic vertebral artery ostial stenosis (VAOS), with respect to tech-nical feasibility and clinical and imaging follow-up results. About 1/4 of the ischemic stroke occurred in the vertebral basilar artery system, especially when in the presence of extracranial proximal vertebral artery stenosis. Extracranial vertebral artery stenosis. Practical textbook aimed at doctors beginning work on a stroke unit or residents embarking on training in stroke care. Found insideThis book was written by expert authors, and detailed epidemiology, etiopathogenesis, mucocutaneous findings, and systemic involvement of Behcet's disease are presented to readers. Diagnosis of VA stenosis by noninvasive imaging techniques is improving and new endovascular and medical treatments are now available. Postoperatively a new Directional Doppler ultrasound examination then showed bilateral normal (= antegrade) vertebral artery blood flow. If you plan to take the Vascular Medicine Board Examination, this book is essential. Carotid Artery Stenosis, Intracranial Artery Stenosis and Vertebral Artery Stenosis If blood clots form, dislodge and flow into the brain, stroke and transient ischemic attacks (TIA) can occur. However, the natural history of VA stenotic lesions is not known and its optimum management is unclear. . We report a case of basilar artery stenosis that was treated using stent- assisted angioplasty. Carotid artery stenosis, vertebral artery stenosis and intracranial artery stenosis are all caused by fatty deposits and cholesterol sticking to the artery walls. How do you repair vertebral artery stenosis? During cervical artery dissection (CAD), arterial blood enters the blood vessel wall through the damaged carotid intima, which separates the intimal and media layers. Some cases of subclavian steal syndrome involve retrograde blood flow in the vertebral artery. The vertebral arteries are located at the back of the neck and merge at the base of the brain to form the basilar artery. The commonest is atherosclerotic disease—the main focus of this review—but others include vertebral artery dissection, fibrous banding in the neck, extrinsic compression in its second and third parts due to trauma of the cervical vertebrae or . Surgery usually is successful technically; however, it is also associated with high rates of procedural and periprocedural complications. Treatment of PAD should include statin . Surgery is the last option for treatment of subclavian artery stenosis. Treatment for spinal stenosis depends on the location of the stenosis and the severity of your signs and symptoms. Surgical treatment Surgery for vertebral artery stenosis can be performed either by endarterectomy or reconstruction. Atherosclerotic vertebral artery disease is often underdiagnosed as a cause of posterior circulation ischemia because of the . partial or complete loss of vision or double vision. Arteries anywhere in the body can become blocked. They receive blood from the aortic arch. Chronic vertebral artery dissections have also been treated by surgical reconstruction to prevent further ischemic or thromboembolic complications, if medical treatment with six month anticoagulation fails or if the dissecting aneurysms and/or high grade stenosis persist 88). Approximately 25% of ischemic strokes involve the vertebrobasilar circulation (, 1,, 2).Vertebral artery (VA) stenosis may account for up to 20% of vertebrobasilar ischemic strokes (, 3-, 7).In an angiographic study of 4748 patients with ischemic stroke, some degree of proximal extracranial VA stenosis was seen in 18% of vessels on the right side of the brain and 22% of vessels . A newer FDA-approved procedure, carotid artery stenting, is a minimally-invasive technique that provides an alternative to surgery. The gold standard in vertebral artery imaging still remains digital subtraction angiography. It causes as many as 20% of posterior circulation stroke. Found insideThis text unifies this body of knowledge into an educational resource capturing the core competencies required of an emergency radiologist. Vertebral artery V1 segments Ref: present vs absent <.001 7.004 2.478 19.793 Vertebral artery V2 segments Ref: present vs absent.836 0.849 0.181 3.989 Vertebral artery V3 segments Ref: present vs . Endarterectomy for atherosclerotic stenosis at the origin and proximal extracranial vertebral artery has been performed via a supraclavicular incision since the early 1960s, with variable success rates. All patients with asymptomatic stenosis at high risk of vascular events should be considered for high-intensity statin therapy, treating to a target LDL-cholesterol level of <1.8 mmol/L (<70 mg/dL). Flow is always antegrade in right vertebral artery (long arrow). This issue of Primary Care: Clinics in Office Practice features expert clinical reviews on Cardiovascular Disease which includes current information on topics such as coronary artery disease, congestive heart failure, atrial fibrillation ... This website uses cookies to ensure you get the best experience on our website. 8,11. Overtime, the tissues of the artery grow around the stent. Our common interest in surgery of the vertebral artery was born in 1976, when as residents in the same hospital, we attended an attempt by two senior surgeons to treat an aneurysm of the vertebral artery at the C 3 level. 3,4 Endovascular treatment with balloon angioplasty alone yields unsatisfactory results . Arteries anywhere in the body can become blocked. Vertebral artery narrowing cannot be treated surgically and has been effectively treated with stenting for many years. It will require not only identification of vertebrobasilar disease but as yet undefined tests to assure symptoms are due to these stenoses. It causes the arteries to narrow, which restricts blood flow to the various parts of the brain. Introduction. Symptomatic VA . Age matters when determining treatment: For patients 75 and older, especially those with other health conditions, the risk of treating carotid artery stenosis may exceed the benefit. Arteries anywhere in the body can become blocked. This includes cardiovascular risk factor modification. However, as far as we know, this study was the first randomized controlled trial that used special cerebrovascular drug-eluting stent for treating vertebral artery stenosis. For example, carotid artery stenosis is a narrowing of the large artery in the neck, the carotid, that supplies oxygen-rich blood to the brain. Place patient in supine and perform a passive extension and side flexion of the head and neck. Citalopram. The vertebral arteries supply blood to the back of the brain and if narrowing (stenosis) of the artery occurs there is a risk of causing stroke. As we age, hypertension and small injuries to the blood vessel wall can allow plaque to build up. Background. What causes narrowing of the vertebral artery? Found insideIt provides clinical information for diagnosis and appropriate care for the patient, resulting in the perfect comprehensive text for spine surgeons. Always follow your healthcare professional's instructions. Blocked arteries in the brain pose special challenges. Covering clinical assessment, techniques and devices, medical treatment, and more, Angioplasty and Stenting of the Carotid and Supra-Aortic Trunks reviews the state of the art in CAS. Found insideThis book is a printed edition of the Special Issue "Diagnosis and Treatment of Thoracic Outlet Syndrome" that was published in Diagnostics Found insideThis book covers all aspects and the most vibrant topics of ischemic stroke research: from basic sciences to latest methods of clinical applications. Editor's Choice - Management of atherosclerotic carotid and vertebral artery disease: 2017 clinical practice guidelines of the European Society for Vascular . For example, carotid artery stenosis is a narrowing of the large artery in the neck, the carotid, that supplies oxygen-rich blood to the brain. The left AICA arises from the left PICA. Vertebral artery occlusions fall under the umbrella of Vertebrobasilar Disease (VBD), otherwise known as Vertebrobasilar Insufficiency (VBI). Patients with vascular disease offer great challenges to physicians of multiple backgrounds. Naylor AR, Ricco JB, de Borst GJ, et al. Patient 6. Subclavian artery - Wikipedia Even in May of 2020, it is still not very clear how to treat patients with stenosis of the vertebral artery. If your symptoms are mild or you aren't experiencing any, your doctor may monitor your condition with regular follow-up appointments. Surgery. 0 cerebral artery stenosis patients report no depressed mood (0%) What people are taking for it. Vertebral artery stenosis (VAS) is mainly caused by atherosclerosis and may occur extracranially or intracranially [].VAS can lead to hypoperfusion, plaque rupture, and subsequent embolization in the vertebrobasilar territory, causing ischemic events, such as transient ischemic attack (TIA) and infarction [2, 3].By comparing 232 patients with posterior cerebral artery (PCA) infarction to 1355 . Vertebrobasilar insufficiency (VBI) is defined by inadequate blood flow through the posterior circulation of the brain, supplied by the 2 vertebral arteries that merge to form the basilar artery. Background: Vertebral artery (VA) stenosis as a cause of ischemic events and its surgical treatment is an overlooked subject. Atherosclerosis is the buildup of cholestero l , fat and other substances traveling through the bloodstream, such as inflammatory cells, cellular waste products, proteins and calcium. The main options for treating narrowing of the arteries in the brain are: This procedure takes place in the angiography suite. Angioplasty using drug-coated balloons in ostial vertebral artery stenosis u2013 first experiences in a small case seriesBackground: Approximately 20-25% of all ischemic strokes occur in the posterior circulation; and 10-20% of the patients ... A, High-grade stenosis of the origin of the left vertebral artery (arrow ). Found insideThis updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. 4 Vertebral artery (VA) stenosis can be treated with angioplasty and/or stenting. Arteriographic demonstration during life of vertebral artery insufficiency due to rotation and extension of the neck. A, High-grade stenosis of the origin of the left vertebral artery (arrow ). The new artery bypasses the damaged blood vessel and restores healthy blood flow in the brain. 4 Vertebral artery (VA) stenosis can be treated with angioplasty and/or stenting. What is stenosis of the vertebral artery, its causes, symptoms, diagnosis and treatment. The results showed that the cerebrovascular drug-elut-ing stent for the treatment of vertebral artery stenosis was safe, We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. All patients with asymptomatic stenosis at high risk of vascular events should be considered for high-intensity statin therapy, treating to a target LDL-cholesterol level of <70 mg/dL. Restenosis rates are low at 5 years (22%). A new generation of intravascular stents that are flexible enough to navigate the tortuosities of the vertebral artery may provide a new therapeutic approach. Recent evidence suggests that the prevalence of carotid tortuosity is higher than conventionally expected ranging from 18% to 34%. Naylor AR, Ricco JB, de Borst GJ, et al. Blocked arteries in the heart often lead to a person having a heart attack or chest pain. Note bilateral stenosis of the posterior cerebral arteries (arrows) and a stenosis involving the distal left vertebral artery at the vertebrobasilar junction. A thorough procedural guide covering applications of neurosonology to diagnosis, monitoring of cerebrovascular and other neurological diseases. Editor's Choice - Management of atherosclerotic carotid and vertebral artery disease: 2017 clinical practice guidelines of the European Society for Vascular Surgery (ESVS). What happens if the vertebral artery is blocked? Infusion of recombinant tissue plasminogen activator for treatment of basilar artery . Background and Aims:Bilateral intracranial vertebral artery disease (ICVAD) often has poor outcomes. It also supplies blood to two very important regions of the brain: the posterior fossa and the occipital lobes. Key Features: Side-by-side photo and illustration format aids in interpretation of intricate surgical procedures More than 1300 figures elucidate clinical cases from the Barrow Neurological Institute and other centers of neurosurgical ... When it reached the narrowed part of the artery, it is opened up. For example, carotid artery stenosis is a narrowing of the large artery in the neck, the carotid, that supplies oxygen-rich blood to the brain. Previous studies have demonstrated that this technique is safe but is limited by high rates of in-stent stenosis. Objective To evaluate the safety and efficacy of a DCB in patients with severe VAOS. Levy, in Stroke (Sixth Edition), 2016. Surgery for vertebral artery stenosis can be performed either by endarterectomy or reconstruction. This revised and updated edition remains the definitive guide to patterns and syndromes in stroke. What are the symptoms of not having enough blood flow to the brain? Material and methods: This retrospective, single-center study includes 43 symptomatic proximal VA stenosis patients between September 2012 and March 2019. Maxim Mokin, Elad I. Medical treatment is usually the first choice. We investigated the safety and feasibility of stenting of symptomatic vertebral artery stenosis of at least 50%, and assessed the rate of vascular events in the vertebrobasilar supply territory to inform the design of a phase 3 trial. 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